The Empire State Building Partners with Outward Bound on First-Ever, Full Rappel Down the Building for Charity (Photo: Business Wire)
The Empire State Building (https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.esbnyc.com&esheet=53973935&newsitemid=20240506846659&lan=en-US&anchor=Empire+State+Building&index=1&md5=580518e0d0a029e7e6a4207573ea5162) (ESB) hosted 20 brave supporters of Outward Bound - along with participant Jared Leto - in a historic rappel down the building’s south façade, in partnership with Outward Bound to raise transformational funds for the charity across the world. Participants total donations exceeded $3 million to Outward Bound, which will make a profound difference in the educational journeys of young people everywhere.
“The Empire State Building is the perfect host to amplify Outward Bound’s charitable mission through this historic rappel, and it reaffirms the Empire State Building’s long-held status as a symbol of hope, strength, and resilience,” said Tony Malkin, chairman and CEO of Empire State Realty Trust. “My wife and I chose to join the Big Rappel to benefit a great cause, and I got to see the amazing views from the three levels of our Observatory and the Empire State Building’s few remaining great office leasing opportunities on the way down!”
Leto kicked off the Big Rappel, that spanned nearly 900 feet from the building’s iconic spire down to the 30th floor. Leto famously climbed (https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.esbnyc.com%2Fblog%2Fjared-leto-climbs-empire-state-building&esheet=53973935&newsitemid=20240506846659&lan=en-US&anchor=famously+climbed&index=2&md5=a399f112cb09c72546672f0c37b82d13) the “World’s Most Famous Building” in November 2023.
This morning, the Empire State Building hosted a lighting ceremony with Her Royal Highness Princess Beatrice, Trustee of Outward Bound in the UK, who flipped the famous switch. Tonight, at sunset, the Empire State Building will shine in blue, pink, green, and white to honor Outward Bound and their important work with young people and the Big Rappel at the Empire State Building. Text CONNECT to 274-16 to receive real-time information about the Empire State Building’s tower lights.
“On behalf of Outward Bound, thank you to the Empire State Building for hosting such an inspirational event. Bringing young people out of their comfort zones and supporting them to achieve something they never thought possible is what Outward Bound is all about. I am so happy to offer my support as a trustee and a great admirer of the Outward Bound Trust and all they stand for - these participants really are an inspiration,” said Her Royal Highness Princess Beatrice.
Outward Bound is a worldwide educational and charitable network whose mission is to change young people’s lives through challenge, learning, and adventure. Four Outward Bound organizations - which include Outward Bound International, The Outward Bound Trust, Outward Bound USA, and NYC Outward Bound Schools - united to create this once-in-a-lifetime event.
“Outward Bound has supported young people to push through and challenge themselves for the last 85 years, and the participants of the Big Rappel show that appetite for adventure in abundance,” said Martin Davidson, CEO, The Outward Bound Trust UK. “In the UK, The Trust inspires thousands of young people every year to achieve something they never thought possible by taking them from inner city environments into our national parks where they experience the extraordinary and learn what they are truly capable of.”
The Empire State Building Observatory recently underwent a $165 million reimagination that included the addition of a dedicated visitor entrance, an immersive museum with nine galleries, brand-new, bespoke Observatory Host uniforms, and a new 102nd Floor Observatory with unmatched view. The reimagined Observatory Experience was voted the number one attraction in the U.S. by Tripadvisor travelers for two consecutive years.
Hi-res imagery and video can be found here (https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fesrtreit.bynder.com%2Fshare%2F6EE2F79A-9F56-418B-B6FC4FD1660019D4%2F%3FviewType%3Dgrid&esheet=53973935&newsitemid=20240506846659&lan=en-US&anchor=here&index=3&md5=b5966583217924066cc5059f023acb36). More information about the Empire State Building can be found online (https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.esbnyc.com&esheet=53973935&newsitemid=20240506846659&lan=en-US&anchor=online&index=4&md5=5c0bf65d25be62dc293aa6ebb6a63634).
About the Empire State Building
The Empire State Building, the “World’s Most Famous Building,” owned by Empire State Realty Trust, Inc. (ESRT: NYSE), soars 1,454 feet above Midtown Manhattan from base to antenna. The $165 million reimagination of the Empire State Building Observatory Experience creates an all-new experience with a dedicated guest entrance, an interactive museum with nine galleries, and a redesigned 102nd Floor Observatory with floor-to-ceiling windows. The journey to the world-famous 86th Floor Observatory, the only 360-degree, open-air observatory with views of New York and beyond, orients visitors for their entire New York City experience and covers everything from the building’s iconic history to its current place in pop culture. The Empire State Building Observatory Experience welcomes millions of visitors each year and was declared “America’s Favorite Building” by the American Institute of Architects, the world’s most popular travel destination by Uber, the #1 attraction in the US for the second year in a row in Tripadvisor’s 2023 Travelers’ Choice Awards: Best of the Best, and the #1 New York City attraction in Lonely Planet’s Ultimate Travel List.
Since 2011, the building has been fully powered by renewable wind electricity, and its many floors house a diverse array of office tenants such as LinkedIn and Shutterstock, as well as retail options like STATE Grill and Bar, Tacombi, and Starbucks. For more information and Observatory Experience tickets visit esbnyc.com or follow the building’s Facebook, X (formerly Twitter), Instagram, Weibo, YouTube, or TikTok.
Source: Empire State Realty Trust
Category: Observatory
View source version on businesswire.com: https://www.businesswire.com/news/home/20240506846659/en/
언론연락처: Empire State Realty Trust, Inc. Jamie Steinberg 212-400-3339
이 뉴스는 기업·기관·단체가 뉴스와이어를 통해 배포한 보도자료입니다.Kirin Holdings Company, Limited (Kirin Holdings)(TOKYO:2503) and National Institute of Infectious Diseases (NIID) are jointly conducting studies to investigate the protective efficacy of L. lactis strain Plasma [postbiotic] (LC-Plasma) immunization against infectious diseases. We now announce that a proposal for our collaborative research has currently been accepted as a project for research and development into new modalities contributing to vaccine development by the Strategic Center of Biomedical Advanced Vaccine Research and Development for Preparedness and Response (SCARDA) in the Japan Agency for Medical Research and Development (AMED).
· Information on the Research Project
Title: Development of an intranasal Lactococcus lactis strain Plasma vaccine inducing innate memory
Representative: Tetsuro Matano, Deputy Director-General, NIID
Representative: Daisuke Fujiwara, Executive Officer, General Manager, Health Science Institute, Kirin Holdings
· Unique point
This research aims at developing an intranasal LC-Plasma vaccine to induce innate immunity for prevention of respiratory virus infection.
Backgrounds
SCARDA was established at AMED in March, 2022, based on the national strategy, to strengthen strategic research funding and to promote the formation of world-class research and development centers (https://www.amed.go.jp/en/program/list/21/index.html). SCARDA is supporting Research & Development for new generation vaccines. Traditional vaccines are expected to induce adaptive immune responses including antibody and T cell responses to prevent infection with pathogens such as viruses and bacteria. Recently, the concept of trained immunity has been discussed and there have been several attempts to develop vaccines inducing effective innate responses against infectious diseases, which has not yet been achieved.
LC-Plasma is characterized by its ability to activate plasmacytoid dendritic cells (pDCs) and stimulate interferon production, leading to enhancement of innate immune responses. Through joint research with NIID, Kirin Holdings has confirmed that SARS-CoV-2 replication is inhibited by the culture supernatants of pDCs stimulated with LC-Plasma (Ishii et al, BBRC 662:26, 2023).
Kirin Holdings and NIID are now conducting collaborative research for the development of vaccines inducing innate immune responses against respiratory virus infection by utilizing LC-Plasma for medical use. This project is to explore the potential of intranasal LC-Plasma vaccination to prevent respiratory infection with viruses including SARS-CoV-2 and influenza viruses.
About Kirin Holdings
Kirin Holdings Company, Limited is an international company that operates in the Food & Beverages domain (Food & Beverages businesses), Pharmaceuticals domain (Pharmaceuticals businesses), and Health Science domain (Health Science business), both in Japan and across the globe.
Kirin Holdings can trace its roots to Japan Brewery which was established in 1885. Japan Brewery became Kirin Brewery in 1907. Since then, the company expanded its business with fermentation and biotechnology as its core technologies, and entered the pharmaceutical business in the 1980s, all of which continue to be global growth centers. In 2007, Kirin Holdings was established as a pure holding company and is currently focusing on boosting its Health Science domain.
Under the Kirin Group Vision 2027 (KV 2027), a long-term management plan launched in 2019, the Kirin Group aims to become A global leader in CSV*, creating value across our world of Food & Beverages to Pharmaceuticals. Going forward, the Kirin Group will continue to leverage its strengths to create both social and economic value through its businesses, with the aim of achieving sustainable growth in corporate value.
* Creating Shared Value. Combined added value for consumers as well as for society at large.
View source version on businesswire.com: https://www.businesswire.com/news/home/20240507111790/en/
언론연락처: Kirin Holdings Company, Limited Corporate Communication Department +81-3-6837-7028 National Institute of Infectious Diseases +81-3-5285-1111
이 뉴스는 기업·기관·단체가 뉴스와이어를 통해 배포한 보도자료입니다.기린 홀딩스(Kirin Holdings Company, Limited)(도쿄증권거래소: 2503)와 국립감염병연구소(National Institute of Infectious Diseases, NIID)가 L. 락티스(L. lactis) 균주 플라즈마 [포스트바이오틱](LC-플라즈마) 면역의 감염병 예방 효과를 조사하는 공동 연구를 진행하고 있다. 이 공동 연구에 대한 제안서가 일본의료연구개발기구(Japan Agency for Medical Research and Development, AMED) 산하 생물의학 첨단 백신 준비 및 대응 연구개발 전략센터(Strategic Center of Biomedical Advanced Vaccine Research and Development for Preparedness and Response, SCARDA)의 백신 개발에 기여할 수 있는 새로운 모달리티 연구 개발을 위한 프로젝트로 최근 수락되었다.
· 연구 프로젝트에 대한 정보
제목: 선천적 기억을 유도하는 비강 내 락토코커스 락티스 균주 혈장 백신 개발
담당자: 마타노 테쓰로(Tetsuro Matano), NIID 사무차장
담당자: 후지와라 다이스케(Daisuke Fujiwara), 기린 홀딩스 건강 과학 연구소(Health Science Institute) 최고책임자, 전무
·고유한 특징
이 연구의 목표는 호흡기 바이러스 감염 예방을 위한 선천성 면역을 유도하기 위한 비강 내 LC-플라즈마 백신을 개발하는 것이다.
설립 배경
SCARDA는 국가 전략에 따라 2022년 3월 AMED에 설립되었으며, 전략적 연구 기금을 강화하고 세계적 수준의 연구 개발 센터 설립을 촉진한다(https://www.amed.go.jp/en/program/list/21/index.html). SCARDA는 차세대 백신을 위한 연구 개발을 지원하고 있다. 기존 백신은 항체 및 T세포 반응을 포함한 적응성 면역 반응을 유도하여 바이러스 및 박테리아와 같은 병원체의 감염을 예방하는 효능을 예상한다. 최근에는 훈련된 면역(trained immunity)이라는 개념이 논의되고 있으며, 감염성 질환에 대한 효과적인 선천적 반응을 유도하는 백신을 개발하려는 여러 시도가 있었지만 아직 성공하지 못했다.
LC-플라즈마는 플라스마사이토이드 수지상 세포(plasmacytoid dendritic cell, pDC)를 활성화하고 인터페론 생성을 자극하여 선천성 면역 반응을 강화하는 것이 특징이다. 기린 홀딩스는 NIID와의 공동 연구를 통해 LC-플라즈마로 자극한 pDC의 배양 상청액이 SARS-CoV-2 복제를 억제한다는 사실을 확인했다(이시이(Ishii) 외, BBRC 662:26, 2023).
기린 홀딩스와 NIID는 현재 의료용 LC-플라즈마를 활용하여 호흡기 바이러스 감염에 대한 선천성 면역 반응을 유도하는 백신 개발을 위한 공동 연구를 진행하고 있다. 이 프로젝트는 SARS-CoV-2 및 인플루엔자 바이러스를 포함한 바이러스의 호흡기 감염을 예방하기 위한 비강 내 LC-플라즈마 백신 접종의 잠재력을 탐구하기 위한 것이다.
기린 홀딩스 소개
기린 홀딩스 컴퍼니는 일본과 전 세계에서 식음료 영역(식품 및 음료 비즈니스), 제약 영역(제약 비즈니스) 및 건강 과학 영역(건강 과학 비즈니스)를 운영하는 국제적 기업이다.
기린 홀딩스의 뿌리는 1885년에 설립된 재팬 브루어리(Japan Brewery)로 거슬러 올라간다. 재팬 브루어리는 1907년에 기린 브루어리가 되었다. 이후 이 회사는 발효와 생명공학을 핵심 기술로 삼아 사업을 확장했고, 1980년대에는 제약 사업에 진출하였으며 이 모두는 계속 글로벌 성장 센터의 역할을 하고 있다. 기린 홀딩스는 2007년 순수 지주회사로 출범해 현재 건강 과학 영역 강화에 주력하고 있다.
2019년에 시작된 장기 경영 계획인 기린 그룹 비전 2027(Kirin Group Vision 2027)(KV 2027)의 기치 아래 기린 그룹은 CSV[*]의 글로벌 리더가 되어 식음료부터 제약까지 우리가 만든 세계 속에서 가치를 창출하는 것을 목표로 한다. 앞으로 기린 그룹은 기업 가치의 지속 가능한 성장을 목표로 기업의 강점을 활용하여 비즈니스를 통해 사회적, 경제적 가치를 창출해 나갈 것이다.
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