Towards the Development of a Vaccine to prevent Respiratory Virus Infection

 

The Empire State Building (https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.esbnyc.com&esheet=53973935&newsitemid=20240506846659&lan=en-US&anchor=Empire+State+Building&index=1&md5=580518e0d0a029e7e6a4207573ea5162) (ESB) hosted 20 brave supporters of Outward Bound - along with participant Jared Leto - in a historic rappel down the building’s south façade, in partnership with Outward Bound to raise transformational funds for the charity across the world. Participants total donations exceeded $3 million to Outward Bound, which will make a profound difference in the educational journeys of young people everywhere.

“The Empire State Building is the perfect host to amplify Outward Bound’s charitable mission through this historic rappel, and it reaffirms the Empire State Building’s long-held status as a symbol of hope, strength, and resilience,” said Tony Malkin, chairman and CEO of Empire State Realty Trust. “My wife and I chose to join the Big Rappel to benefit a great cause, and I got to see the amazing views from the three levels of our Observatory and the Empire State Building’s few remaining great office leasing opportunities on the way down!”

Leto kicked off the Big Rappel, that spanned nearly 900 feet from the building’s iconic spire down to the 30th floor. Leto famously climbed (https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.esbnyc.com%2Fblog%2Fjared-leto-climbs-empire-state-building&esheet=53973935&newsitemid=20240506846659&lan=en-US&anchor=famously+climbed&index=2&md5=a399f112cb09c72546672f0c37b82d13) the “World’s Most Famous Building” in November 2023.

This morning, the Empire State Building hosted a lighting ceremony with Her Royal Highness Princess Beatrice, Trustee of Outward Bound in the UK, who flipped the famous switch. Tonight, at sunset, the Empire State Building will shine in blue, pink, green, and white to honor Outward Bound and their important work with young people and the Big Rappel at the Empire State Building. Text CONNECT to 274-16 to receive real-time information about the Empire State Building’s tower lights.

“On behalf of Outward Bound, thank you to the Empire State Building for hosting such an inspirational event. Bringing young people out of their comfort zones and supporting them to achieve something they never thought possible is what Outward Bound is all about. I am so happy to offer my support as a trustee and a great admirer of the Outward Bound Trust and all they stand for - these participants really are an inspiration,” said Her Royal Highness Princess Beatrice.

Outward Bound is a worldwide educational and charitable network whose mission is to change young people’s lives through challenge, learning, and adventure. Four Outward Bound organizations - which include Outward Bound International, The Outward Bound Trust, Outward Bound USA, and NYC Outward Bound Schools - united to create this once-in-a-lifetime event.

“Outward Bound has supported young people to push through and challenge themselves for the last 85 years, and the participants of the Big Rappel show that appetite for adventure in abundance,” said Martin Davidson, CEO, The Outward Bound Trust UK. “In the UK, The Trust inspires thousands of young people every year to achieve something they never thought possible by taking them from inner city environments into our national parks where they experience the extraordinary and learn what they are truly capable of.”

The Empire State Building Observatory recently underwent a $165 million reimagination that included the addition of a dedicated visitor entrance, an immersive museum with nine galleries, brand-new, bespoke Observatory Host uniforms, and a new 102nd Floor Observatory with unmatched view. The reimagined Observatory Experience was voted the number one attraction in the U.S. by Tripadvisor travelers for two consecutive years.

Hi-res imagery and video can be found here (https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fesrtreit.bynder.com%2Fshare%2F6EE2F79A-9F56-418B-B6FC4FD1660019D4%2F%3FviewType%3Dgrid&esheet=53973935&newsitemid=20240506846659&lan=en-US&anchor=here&index=3&md5=b5966583217924066cc5059f023acb36). More information about the Empire State Building can be found online (https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.esbnyc.com&esheet=53973935&newsitemid=20240506846659&lan=en-US&anchor=online&index=4&md5=5c0bf65d25be62dc293aa6ebb6a63634).

About the Empire State Building

The Empire State Building, the “World’s Most Famous Building,” owned by Empire State Realty Trust, Inc. (ESRT: NYSE), soars 1,454 feet above Midtown Manhattan from base to antenna. The $165 million reimagination of the Empire State Building Observatory Experience creates an all-new experience with a dedicated guest entrance, an interactive museum with nine galleries, and a redesigned 102nd Floor Observatory with floor-to-ceiling windows. The journey to the world-famous 86th Floor Observatory, the only 360-degree, open-air observatory with views of New York and beyond, orients visitors for their entire New York City experience and covers everything from the building’s iconic history to its current place in pop culture. The Empire State Building Observatory Experience welcomes millions of visitors each year and was declared “America’s Favorite Building” by the American Institute of Architects, the world’s most popular travel destination by Uber, the #1 attraction in the US for the second year in a row in Tripadvisor’s 2023 Travelers’ Choice Awards: Best of the Best, and the #1 New York City attraction in Lonely Planet’s Ultimate Travel List.

Since 2011, the building has been fully powered by renewable wind electricity, and its many floors house a diverse array of office tenants such as LinkedIn and Shutterstock, as well as retail options like STATE Grill and Bar, Tacombi, and Starbucks. For more information and Observatory Experience tickets visit esbnyc.com or follow the building’s Facebook, X (formerly Twitter), Instagram, Weibo, YouTube, or TikTok.

Source: Empire State Realty Trust
Category: Observatory

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언론연락처: Empire State Realty Trust, Inc. Jamie Steinberg 212-400-3339

이 뉴스는 기업·기관·단체가 뉴스와이어를 통해 배포한 보도자료입니다.Kirin Holdings Company, Limited (Kirin Holdings)(TOKYO:2503) and National Institute of Infectious Diseases (NIID) are jointly conducting studies to investigate the protective efficacy of L. lactis strain Plasma [postbiotic] (LC-Plasma) immunization against infectious diseases. We now announce that a proposal for our collaborative research has currently been accepted as a project for research and development into new modalities contributing to vaccine development by the Strategic Center of Biomedical Advanced Vaccine Research and Development for Preparedness and Response (SCARDA) in the Japan Agency for Medical Research and Development (AMED).

· Information on the Research Project
Title: Development of an intranasal Lactococcus lactis strain Plasma vaccine inducing innate memory
Representative: Tetsuro Matano, Deputy Director-General, NIID
Representative: Daisuke Fujiwara, Executive Officer, General Manager, Health Science Institute, Kirin Holdings

· Unique point
This research aims at developing an intranasal LC-Plasma vaccine to induce innate immunity for prevention of respiratory virus infection.

Backgrounds
SCARDA was established at AMED in March, 2022, based on the national strategy, to strengthen strategic research funding and to promote the formation of world-class research and development centers (https://www.amed.go.jp/en/program/list/21/index.html). SCARDA is supporting Research & Development for new generation vaccines. Traditional vaccines are expected to induce adaptive immune responses including antibody and T cell responses to prevent infection with pathogens such as viruses and bacteria. Recently, the concept of trained immunity has been discussed and there have been several attempts to develop vaccines inducing effective innate responses against infectious diseases, which has not yet been achieved.

LC-Plasma is characterized by its ability to activate plasmacytoid dendritic cells (pDCs) and stimulate interferon production, leading to enhancement of innate immune responses. Through joint research with NIID, Kirin Holdings has confirmed that SARS-CoV-2 replication is inhibited by the culture supernatants of pDCs stimulated with LC-Plasma (Ishii et al, BBRC 662:26, 2023).

Kirin Holdings and NIID are now conducting collaborative research for the development of vaccines inducing innate immune responses against respiratory virus infection by utilizing LC-Plasma for medical use. This project is to explore the potential of intranasal LC-Plasma vaccination to prevent respiratory infection with viruses including SARS-CoV-2 and influenza viruses.

About Kirin Holdings

Kirin Holdings Company, Limited is an international company that operates in the Food & Beverages domain (Food & Beverages businesses), Pharmaceuticals domain (Pharmaceuticals businesses), and Health Science domain (Health Science business), both in Japan and across the globe.

Kirin Holdings can trace its roots to Japan Brewery which was established in 1885. Japan Brewery became Kirin Brewery in 1907. Since then, the company expanded its business with fermentation and biotechnology as its core technologies, and entered the pharmaceutical business in the 1980s, all of which continue to be global growth centers. In 2007, Kirin Holdings was established as a pure holding company and is currently focusing on boosting its Health Science domain.

Under the Kirin Group Vision 2027 (KV 2027), a long-term management plan launched in 2019, the Kirin Group aims to become A global leader in CSV*, creating value across our world of Food & Beverages to Pharmaceuticals. Going forward, the Kirin Group will continue to leverage its strengths to create both social and economic value through its businesses, with the aim of achieving sustainable growth in corporate value.

* Creating Shared Value. Combined added value for consumers as well as for society at large.

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언론연락처: Kirin Holdings Company, Limited Corporate Communication Department +81-3-6837-7028 National Institute of Infectious Diseases +81-3-5285-1111

이 뉴스는 기업·기관·단체가 뉴스와이어를 통해 배포한 보도자료입니다.[대한행정일보]